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O'Keeffe's

O'Keeffe's

Hardworking Skincare

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Health & Wellness

About the Brand

About

For over a quarter-century, O'Keeffe's has been on a mission to provide relief so you can keep going. Our story is one of dedication, innovation, and a deep understanding of what hard-working hands and feet truly need.

Founding Story

O'Keeffe's was born out of necessity and compassion. More than 25 years ago, Tara O'Keeffe, a pharmacist, saw her father Bill struggling with dry, cracked hands. Bill, a rancher and diabetic, couldn't find any product that provided the relief he desperately needed.

Determined to help her father, Tara took matters into her own hands. She began experimenting in her kitchen. The result of her efforts would become what we now know as Working Hands. Tara's homemade hand cream wasn't just effective – it was life-changing for her father. The formula she created in her kitchen provided the relief Bill had been searching for. But the story doesn't end there.

Word began to spread about this remarkable cream. People started asking for it, recognizing its effectiveness. What started as a solution to keep her father working, became a household name for many others struggling with dry, cracked skin.

Signature Products

Tap a product to view details and request a sample.

Hardworking Body Lotion

O'Keeffe's

Health & Wellness / Dermatology

Replies in ~3 days Women Owned & Founded
Healthy Feet Heel Repair Kit

O'Keeffe's

Health & Wellness / Dermatology

Replies in ~3 days Holiday Gifts · Women Owned & Founded
Healthy Feet Intense Renewal - 3 oz

O'Keeffe's

Health & Wellness / Personal Hygiene

Replies in ~3 days Women Owned & Founded
Healthy Feet Night Treatment - 3 oz

O'Keeffe's

Health & Wellness / Personal Hygiene

Replies in ~3 days Women Owned & Founded
Healthy Feet Original Jar - 3.2 oz

O'Keeffe's

Health & Wellness / Personal Hygiene

Replies in ~3 days Women Owned & Founded
Healthy Feet Original Tube - 3 oz

O'Keeffe's

Health & Wellness / Personal Hygiene

Replies in ~3 days Holiday Gifts · Women Owned & Founded
Healthy Feet Pain Relief

O'Keeffe's

Health & Wellness / Personal Hygiene

Replies in ~3 days Women Owned & Founded
Lip Repair Cherry & Vitamin E Oil

O'Keeffe's

Health & Wellness / Personal Hygiene

Replies in ~3 days Women Owned & Founded
Lip Repair Cooling

O'Keeffe's

Health & Wellness / Personal Hygiene

Replies in ~3 days Holiday Gifts · Women Owned & Founded
View all 17 products

Showing 9 of 17

Press Coverage

SHE SCRIBES

Aug 23, 2026

Hardworking Relief for Hardworking Hands: Why Millions Trust O’Keeffe’s Every Day

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YAHOO SHOPPING

Jul 5, 2026

42 Personal Care Products Things That Aren't Fancy, But Reviewers Say Just Plain Work

Gloves in a Bottle Shielding Lotion forms an invisible layer around your hands to help guard 'em against drying hand-washing and other common irritants.

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FLOW SPACE

Jan 11, 2026

Gloves in a bottle shielding lotion

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FLOW SPACE

Jan 4, 2025

12 Best Over-the-Counter Moisturizers, Creams, Serums & Balms for Eczema Relief

The article was a round-up of the best over-the-counter moisturizers, creams, balms and serums for eczema relief, specifically targeted toward midlife women (ages 35 - 65) with varying stages of eczema. Each product was tested by staff members aged 35 - 65, experiencing mild to moderate forms of eczema in different areas of the body, with two staffers testing the more heavy duty balms/ointments on active flares. Each product was tested for a minimum of two weeks (or according to instructions). As the senior health editor who recently developed eczema on my left elbow, I personally tested O'Keeffe's Skin Repair Eczema Relief, Gloves In A Bottle Shielding Lotion, Dr. Dan’s Hydrocortisone Hand and Body Lotion and First Aid Beauty Ultra Repair Cream. While the products are listed by number, the numbers do not signify ranking; in fact, each product received its own badge for what it did best. O’Keeffe’s Skin Repair Eczema Relief was crowned "Best Lightweight Daily Moisturizer for Eczema" and Gloves In A Bottle Shielding Lotion was crowned "Best for Irritant Protection & Eczema Prevention."

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AZ BIG MEDIA

Product reviews: Inside this month’s shopping obsessions

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