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We know that once you have tried Replens products you'll love them too. Try it for yourself and see why Replens is the #1 selling long-lasting vaginal moisturizer!

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About the Brand

Replens is different from other lotions or lubricants because it contains a bioadhesive that allows it to attach to dry cells and deliver continuous moisture until those cells are naturally regenerated. This allows vaginal tissues to absorb moisture leaving them hydrated and rejuvenated.

Signature Products

Tap a product to view details and request a sample.

Replens Long-Lasting Vaginal Moisturizer

Replens

Health & Wellness / Women's Health

Responds within 24 hrs
Replens Silky Smooth Silicone-Based Lubricant

Replens

Health & Wellness / Women's Health

Responds within 24 hrs

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Press Coverage

SINGLECARE

Jul 12, 2026

Estrogen cream for vaginal dryness: Does it work, how to use it, and alternatives

Options include vaginal moisturizers such as Replens or lubricants such as Vagisil or KY Jelly. A healthcare provider, such as a primary care provider or OB-GYN, should determine the best treatment based on symptom severity, medical history, and individual preference.

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OTHER

Apr 12, 2026

Is HRT Right For Me?

Hormone therapy (HRT) is the gold standard for treatment of hot flashes, night sweats and other pesky menopausal symptoms that can bedevil women at midlife. But not everyone is a candidate for the therapy experts consider most effective.

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EVERYDAY HEALTH

Mar 12, 2026

What Is Perimenopause?

Perimenopause occurs over several years leading up to menopause, when a person with a uterus and ovaries stops menstruating. This period before the onset of menopause begins when the time between periods becomes erratic and typically lasts four to eight years.[1]

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YAHOO HEALTH

Mar 2, 2026

Do you really need a vaginal moisturizer for menopause? Probably!

You knew menopause would force you to level up your moisturizer game. But should you be moisturizing uh, everywhere? Find out what the experts say.

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EVERYDAY HEALTH

Feb 17, 2026

Symptoms, Causes, Diagnosis, Treatment, and Prevention

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EVERYDAY HEALTH

Feb 17, 2026

Symptoms, Causes, Diagnosis, Treatment, and Prevention

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HEALTHCENTRAL

Jan 27, 2026

Hormone Therapy Alternatives After Breast Cancer

Experts share some of the non-HT options for managing menopause symptoms after breast cancer.

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WOMAN'S WORLD

Jan 8, 2026

How To Prevent Yeast Infections Before They Start This Winter—Ob-Gyn’s $3 Undies Swap, the Best Lube and More

Cold weather can trigger yeast infections. Our experts explain why and how to stop them in their tracks

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YAHOO HEALTH

Dec 18, 2025

The 13 best lubes for menopause, according to experts

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FLOW SPACE

Dec 16, 2025

How Your Vagina & Vulva Change as You Age—In Your 30s, 40s, 50s, 60s &

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FLOW SPACE

Dec 16, 2025

How Your Vagina & Vulva Change as You Age—In Your 30s, 40s, 50s, 60s &

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FLOW SPACE

Dec 16, 2025

How Your Vagina & Vulva Change as You Age—In Your 30s, 40s, 50s, 60s & Beyond

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YAHOO HEALTH

Dec 7, 2025

How to manage menopause symptoms naturally

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YAHOO HEALTH

Dec 7, 2025

How to manage menopause symptoms naturally

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YAHOO HEALTH

Dec 7, 2025

How to manage menopause symptoms naturally

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SECTION HIKER

Nov 10, 2025

50 Best Backpacking Gifts Under $50

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SECTION HIKER

Nov 10, 2025

50 Best Backpacking Gifts Under $50

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WOMAN'S WORLD

Sep 18, 2025

Vaginal Dryness After 50? It May Be GSM—See the Signs and Treatment

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WOMAN'S WORLD

Sep 18, 2025

Vaginal Dryness After 50? It May Be GSM—See the Signs and Treatment

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WOMAN'S WORLD

Sep 18, 2025

Vaginal Dryness After 50? It May Be GSM—See the Signs and Treatment Options

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FLOW SPACE

Sep 9, 2025

What Is Genitourinary Syndrome of Menopause (GSM)?

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FLOW SPACE

Sep 9, 2025

What Is Genitourinary Syndrome of Menopause (GSM)?

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FLOW SPACE

Sep 9, 2025

What Is Genitourinary Syndrome of Menopause (GSM)?

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WOMAN'S WORLD

Sep 8, 2025

5 Natural Remedies for Vaginal Dryness That Doctors Say Really Work

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YAHOO HEALTH

Sep 8, 2025

5 Natural Vaginal Dryness Remedies That Doctors Say Work

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WOMAN'S WORLD

Sep 8, 2025

5 Natural Remedies for Vaginal Dryness That Doctors Say Really Work

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YAHOO HEALTH

Sep 8, 2025

5 Natural Vaginal Dryness Remedies That Doctors Say Work

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WOMAN'S WORLD

Sep 8, 2025

5 Natural Remedies for Vaginal Dryness That Doctors Say Really Work

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FLOW SPACE

Jul 16, 2025

Yes, Vaginal Estrogen Really Works — Here’s Where You Can Get It Online

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FLOW SPACE

Jul 16, 2025

Yes, Vaginal Estrogen Really Works — Here’s Where You Can Get It Online

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FLOW SPACE

Jul 16, 2025

Yes, Vaginal Estrogen Really Works — Here’s Where You Can Get It Online

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FLOW SPACE

Jul 16, 2025

Yes, Vaginal Estrogen Really Works — Here’s Where You Can Get It Online

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BUSINESS WIRE

Nov 20, 2024

What's Up Down There? Dr. Streicher Explains Genitourinary Syndrome of Menopause (GSM)

Dr. Lauren Streicher, a leading gynecologist and menopause expert, discusses the widespread issue of genitourinary syndrome of menopause (GSM) in her podcast, sponsored by Replens. She explains the symptoms, such as vaginal dryness and urinary problems, and highlights various treatment options, including Replens Silky Smooth Personal Lubricant and Replens Long-Lasting Vaginal Moisturizer. Dr. Streicher emphasizes the importance of seeking treatment and dispels the myth that these symptoms are a normal part of aging.

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NEW YORK POST

Nov 7, 2024

Ditch the discomfort: How Replens redefines vaginal moisturizers

The article discusses the availability of Replens Long-Lasting Vaginal Moisturizer on Amazon. It highlights the product's features, including its FDA clearance, clinical testing, and bio-adhesive technology, which provides long-lasting hydration without estrogen or fragrance. The moisturizer aims to relieve vaginal dryness and discomfort, offering a convenient and effective solution.

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OPRAH DAILY

Sep 11, 2024

What Happens to Your Vaginal Microbiome During Menopause

The article discusses the impact of menopause on the vaginal microbiome, highlighting how the decline in estrogen leads to a decrease in beneficial lactobacilli bacteria, resulting in symptoms like dryness and painful intercourse. Experts such as Dr. Lauren Streicher and Dr. Kimberly Capone provide insights on maintaining a healthy vaginal microbiome through hormone replacement therapy and over-the-counter products like Replens Long-Lasting Vaginal Moisturizer. The importance of diet and gut health in supporting the vaginal microbiome is also emphasized.

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BYRDIE

Aug 1, 2023

Gynecologists Have One Ask: Please Don't Use Yoni Pearls

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REAL SIMPLE

Jul 16, 2023

You Can't Actually 'Balance' Your Hormones—But You Can Help Manage Their Natural Ups and Downs

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VERYWELL HEALTH

Jul 9, 2023

What Is Lube?

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VERYWELL HEALTH

Jun 30, 2023

Sex in the Senior Years

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HEALTH

May 14, 2023

Editor’s Picks: 9 Vaginal Moisturizers and Lubricants That Ease Vaginal Dryness

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VERYWELL HEALTH

Apr 26, 2023

Vaginal Dryness and Menopause: What You Need to Know

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SHEKNOW

Apr 23, 2023

How Your Vagina & Vulva Change As You Age — 30s, 40s, 50s & Beyond

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WOMEN'S HEALTH

Apr 4, 2023

14 Reasons Your Vagina Is So Damn Itchy, According To Gynecologists

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WOMEN'S HEALTH

Apr 4, 2023

14 Reasons Your Vagina Is So Damn Itchy, According To Gynecologists

There are only a few things in this world that can make you more uncomfortable than having *that area* begging for a good scratch fest. There are a lot of dos and don'ts when it comes to cleaning, of course, but what’s the protocol when vaginal itching is keeping you up at night?

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PREVENTION

Mar 9, 2023

10 Home Remedies for Vaginal Itching That Are Effective, According to Gynecologists

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PREVENTION

Mar 9, 2023

10 Home Remedies for Vaginal Itching That Are Effective, According to Gynecologists

Whether you’re dealing with harsh soaps or a yeast infection, these simple treatments can provide relief.

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LIVESTRONG

Feb 24, 2023

Pain During Sex? Here's What Your Body's Trying to Tell You

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LIVESTRONG

Feb 24, 2023

Pain During Sex? Here's What Your Body's Trying to Tell You

Pain during sex is common, but it's definitely not normal. So if being intimate is making you physically uncomfortable, it's time to get help.

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ROMPER

Jan 29, 2023

Why Is My Vagina Itchy? Experts Explain

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FORBES

Jan 22, 2023

Bleeding After Sex: Everything You Need To Know

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FORBES

Jan 22, 2023

Bleeding After Sex: Everything You Need To Know

It can be unsettling to experience vaginal bleeding after sex—and even more so if you’re pregnant or planning to become pregnant. There are a variety of reasons why you might have some bleeding after sex. Sometimes, it could be as simple as not using enough lubricant during sex. Other times, it could signal an abnormality with your cervical health and may warrant a more in-depth check-in with your doctor.

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PREVENTION

Jan 12, 2023

How to Deal With Vaginal Dryness

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PREVENTION

Jan 12, 2023

How to Deal With Vaginal Dryness

You don’t have to suffer from this very treatable issue.

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